Biochemistry at The Biology Project

B12/Folate Problem set

Question 8: B12deficiency

Abnormal findings in patients with a vitamin B12 deficiency may include:

A. methylmalonic aciduria

B. homocystinuria

C. megaloblastic anemia

D. hypersegmented nuclei in leucocytes

E. sensory neuropathy

All five symptoms

Yes, all five! As you must have realized, a B12 deficiency can also disrupt folate metabolism via the infamous "folate trap", so that the symptoms displayed by the patient are all of the symptoms of B12 and folate deficiency combined.

[Problem 8] [Tutorial]

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January 31, 2000
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