Regulation of Carbohydrate Metabolism Problem Set

Question 5: Enzyme Phosphorylation Induced by Glucagon

The same enzymes that are (de)phosphorylated by insulin action (namely glycogen synthase, glycogen phosphorylase, the PFK-2/FBPase-2 bifunctional enzyme and pyruvate kinase) are phosphorylated via glucagon and/or epinephrine action. Which kinase is responsible for these phosphorylation events?

A.	Protein kinase C
B.	Calmodulin-dependent protein kinase
C.	Protein kinase A
D.	Receptor tyrosine kinase
E.	beta-ARK

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