Biochemistry at The Biology Project

Acids & Bases Problem Set

Question 10: Relationship between pKa and pH

The correct operational relationship between pKa and pH is that:

A. both are log functions.
B. both are always <7 for acids, and >7 for bases.
C. These two concepts are not operationally related in any way since biological fluids contains mixtures of too many acids and bases.
D. When pH = pKa , the compound in question will have a charge of +0.5.
E. When pH = pKa , the ionizable compound in question (whether acid or base) will be half protonated and half deprotonated.
This is in fact the very definition of pKa.

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