DNA Forensics Problem Set 1

Problem 5: VNTR: hypervariable regions

VNTR alleles are hypervariable regions of human DNA that differ from each other in:

A. location of internal sites recognized by restriction enzymes.
B. variable number of point mutations.
C. number of copies of an internally repeated DNA sequence.
A tandem repeat is a short sequence of DNA that is repeated in a head-to-tail fashion at a specific chromosomal locus. Tandem repeats are interspersed throughout the human genome. Some sequences are found at only one site -- a single locus -- in the human genome. For many tandem repeats, the number of repeated units vary between individuals. Such loci are termed VNTRs.
D. variable location on different chromosomes.
E. ability to hybridize with a specific single locus probe.

The Biology Project
University of Arizona
Tuesday, August 20, 1996
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