Human Genetics Problem Set

Problem 2: Using RFLP-analysis to hunt for human genes


When RFLP analysis is used to search for a human gene, the strategy is to first locate?

A. a known gene on the same chromosome
B. an homozygous individual with a simple RFLP pattern
C. a DNA sequence anywhere on the same chromosome
D. any DNA marker co-inherited with the genetic trait of interest
Genes and anonymous DNA markers that are located near each other on the same chromosome are "linked," and do not segregate independently during meiosis.
E. an exon of the disease gene

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Revised: November 5, 1998
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