Human Genetics Problem Set

Problem 15: Markers for mapping chromosomes


Which of the following is a useful marker for genetic or physical mapping of human chromosomes?

A. RFLPs, "restriction fragment length polymorphisms"
B. ESTs, "expressed sequence tags"
C. STRPs, "short tandem repeat polymorphisms"
D. STSs, "sequence tagged sites"
E. all of the above
RFLPs are genetic markers detected by Southern hybridization. ESTs, STRPs, and STSs are markers detected by PCR.

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Revised: November 5, 1998
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