Human Genetics Problem Set
Problem 18 Tutorial: DNA expressed as mRNA transcripts
The term "EST" is now used to describe the DNA sequence of a short fragment of a cDNA. As of October 1996, there were about 450,000 EST sequences from human DNA in public DNA sequence databases. Many are redundant cDNAs from different regions of the same mRNA. Nevertheless, approximately 49,000 unique human ESTs are known, representing half of the predicted 100,000 expressed sequences in the human genome.
University of Arizona
Revised: November 5, 1998
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