Antibody Structure Problem Set

Problem 5. Antibody/antigen binding


Glutamine 121 protrudes away from the surface of the antigen. The exposed residue can fit into a depression in the antibody. Association leads to the formation of __________ between antigen and antibody?

A. covalent bonds
B. ionic bonds
C. hydrophobic attractions

hydrogen bonds

The antigen’s Gln 121 fits into a depression created by the 3-D structure of the antibody; this antibody/antigen interaction is stabilized by multiple hydrogen bonds.

The Biology Project
The University of Arizona
Tuesday, June 20, 2000
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