The Biology Project: Immunology

Introduction to Immunology

Problem 6. Antigen combining sites

If a B cell clone began to produce antibody with altered binding strength and specificity for antigen, you would expect the mutation of the antibody gene to involve:

A. The variable region of the heavy chain or the constant region of the light chain
B. The variable region of the light chain or the constant region of the heavy chain
C.

The variable regions of the light or heavy chains

The variable coding regions of both light and heavy chains determine antigen specificity.
D. The constant regions of the light or heavy chains

 

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The Biology Project > Immunology > Immunology Problem Set