The Biology Project: Immunology

Introduction to Immunology

Problem 8. Cellular immunity


Epstein Barr virus (EBV) infects endothelial cells and B cells. About half of us are infected by the virus while very young, and do not suffer disease. Around half of individuals who avoid the virus while young are infected in the teenage years and develop a disease called mononucleosis. In this disease, lymph nodes swell painfully as our immune system produces large numbers of lymphocytes to eliminate virus-producing cells. These lymphocytes are probably:

A. B cells which produce antibody eliminating virus-infected cells

Cytotoxic T cells to destroy virus-containing cells

Specific cytotoxic T cells can become nearly half of the T cells in an infected person's body. These cells eventually deplete the virus by removing infected cells.
C. Helper T cells which stimulate B cell clonal selection
D. Granulocytes which invade areas of virus production


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