Monohybrid Cross Problem Set

Genetics is the study of heredity and variation in organisms. We begin with a study of the monohybrid cross, invented by Mendel. In a monohybrid cross, organisms differing in only one trait are crossed. Our objective is to understand the principles that govern inheritance in plants and animals, including humans, by solving problems related to the monohybrid cross.

Instructions: The following problems have multiple choice answers. Correct answers are reinforced with a brief explanation. Incorrect answers are linked to tutorials to help solve the problem.

  1. The monohybrid cross
  2. Mendel's first law
  3. Mendel's "Experiment 1"
  4. A cross of F1-hybrid plants
  5. Another F1-hybrid cross
  6. Predicting the dominant allele
  7. The test cross
  8. Predicting the results of a test cross
  9. Incomplete dominance
  10. Disappearance of parental phenotypes in the F1-generation
  11. Codominant alleles: The human ABO markers
  12. 2:1 segregation in Manx cats
  13. Predicting human blood types


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Department of Biochemistry and Molecular Biophysics
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Thursday, October 1, 1998
Revised: November 2004
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