Sex-Linked Inheritance Problem Set

Problem 6: Hemophilia in humans

Tutorial to help answer the question

Hemophilia in humans is due to an X-chromosome mutation. What will be the results of mating between a normal (non-carrier) female and a hemophilac male?


Genotypes and phenotypes of parents

The eggs of the mother will all contain the normal X chromosome.

The sperm of the father will contain either the X chromosome with the mutation causing hemophilia or the Y chromosome.

Genotypes and phenotypes of offspring

All of the daughters inherit an X chromosome with the mutation from their father, and will be carriers.

All the sons inherit a normal X from the mother.

The Biology Project
University of Arizona
Updated: July 15, 1999
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