Molecular Genetics of Prokaryotes Problem Set
Problem 12: Effect of high glucose concentrationsTutorial to help answer the question
An E. coli cell is grown in the presence of high amounts of glucose. Which of the following is true?
Cyclic AMP synthesized from ATPControl of the rate of transcription of an operons for catabolic enzymes such as the lac operon is regulated through intracellular levels of 3'-5'-cyclic adenosine monophosphate, or cAMP. cAMP is synthesized from ATP by the enzyme adenyl cyclase.
The intracellular level of cAMP is in turn regulated by the intracellular concentration of glucose. As glucose levels fall, cAMP levels rise. As glucose levels rise, cAMP levels fall.
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Updated: July 15, 1999
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