Nucleic Acids and the Genetic Material Problem Set 1

Problem 1: DNA, the genetic material

Which scientists first gave experimental evidence that DNA is the genetic material?

A Avery, MacLeod, and McCarty who repeated the transformation experiments of Griffith, and chemically characterized the transforming principle.
B Garrod, who postulated that Alcaptonuria, or black urine disease, was due to a defective enzyme.
C Beadle and Tatum, who used a mutational and biochemical analysis of the bread mold Neurospora to establish a direct link between genes and enzymes.
D Meselson and Stahl who showed that DNA is replicated semiconservatively.
E Watson and Crick who gave a model for the structure of DNA

The Biology Project
University of Arizona
Thursday, October 3, 1996
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